Transcranial Magnetic Stimulation

Migraine is often described as an electrical storm, in which the brain is hyperexcitable with an abnormal response to normal stimuli or triggers. The result can be an excruciatingly painful headache. Clinical research has shown that a brief pulse of energy, such as transcranial magnetic stimulation (TMS), may be effective in interrupting or short-circuiting the progression of migraine.

TMS Technology

TMS technology has been used for many years to study the brain. The most robust and widely accepted use is in measuring the connection between the primary motor cortex and muscles. This is most useful in monitoring stroke, spinal cord injury, multiple sclerosis and motor neuron disease. TMS is based on the principles of induction—rapidly changing magnetic fields that induce electrical currents. When TMS is applied to the back of the head, a magnetic field of very short duration passes through the skull and tissue non-invasively and without discomfort. The magnetic field induces very mild electrical currents in the brain tissue to excite and depolarize neurons in the brain. This process is thought to interrupt the abnormal electrical activity associated with migraine and cortical spreading depression (CSD).

eNeura sTMS Technology

eNeura technology utilizes single-pulse Transcranial Magnetic Stimulation, or sTMS. The SpringTMS® Total Migraine System delivers each treatment in a millisecond (1/1,000 of a second). By comparison, a typical magnetic resonance imaging (MRI) device continuously delivers a magnetic field that is more than twice as strong, and with each session lasting more than 20 minutes. Two decades of clinical experience with sTMS has consistently demonstrated it to be a non-significant risk technology, with promise in the diagnosis, monitoring and treatment of neurological and psychiatric disease in adults.1-3

REFS:

1. Anand S, Hotson J. Transcranial magnetic stimulation: Neurophysiological applications and safety. Brain and Cognition. 2002;50:366-386.

2. Rossini PM, Rossi S. Transcranial magnetic stimulation: diagnostic, therapeutic, and research potential. Neurology. 2007;68:484-488.

3. Wassermann EM, Lisanby S. Therapeutic application of repetitive transcranial magnetic stimulation: a review. Clin Neurophysiol. 2001;112:1367-1377.

For U.S. Residents: CAUTION - Federal law limits the SpringTMS device to investigational use only. LBL-0022 Rev J