Much more than a bad headache, migraine is a chronic neurological disease with significant impact on individuals and on society as a whole. It affects more than 10% of the population worldwide.2
Migraine patients generally experience symptomatic episodes 2 to 4 times monthly, during which more than half of them report serious functional impairment or require bed rest.4
While the precise cause of migraine is unknown, it is believed to be the result of overstimulation or hyperexcitability in the part of the brain that controls sensory processing.5
Common symptoms of migraine include:6
About one-third of patients with migraine also experience visual disturbances—called auras—before the onset of pain.5
Migraine has a troubling impact on society as a whole, resulting in a loss of productivity and an enormous financial burden. The annual economic impact of migraine in the United States is estimated to be nearly $24 billion.7
Patients with migraine often miss out on essential parts of daily life. Family time, important work, and recreation activities can all be disrupted by the symptoms of migraine—and also by the side effects of medications taken to treat migraine.
While the goal of migraine treatment is to help patients get back to their normal daily lives, many of the medications that physicians prescribe to help treat migraine symptoms may not be well-tolerated. They often have their own serious side effects, such as debilitating amounts of drowsiness.
About 70% of migraine patients are not satisfied with or cannot tolerate the side effects associated with medications.3
Patients have long sought a non-drug treatment option for migraine. But there has been no clinically effective and well-tolerated treatment available until now.